Anavar and liver toxicity

Women are almost twice as likely as men to form gallstones especially during the fertile years; the gap narrows after the menopause . The underlying mechanism is female sex hormones; parity, oral contraceptive use and estrogen replacement therapy are established risk factors for cholesterol gallstone formation. Female sex hormones adversely influence hepatic bile secretion and gallbladder function. Estrogens increase cholesterol secretion and diminish bile salt secretion, while progestins act by reducing bile salt secretion and impairing gallbladder emptying leading to stasis. A new 4th generation progestin, drospirenone , used in some oral contraceptives may further heighten the risk of gallstone disease and cholecystectomy; however, the increased risk is quite modest and not likely to be clinically meaningful. [3]

Anabolic steroids differ in their characteristics, which means there are steroids that are only suitable for specific uses. For instance, Trenbolone is not recommended for bulking but it is an outstanding fat burner. This makes it perfect for a lean mass cycle or a cutting cycle. Always take the side effects of a particular compound into consideration whenever you plan a stack. Do not combine anabolic steroids that show similar side effects. For example, never combine Anapolon and Dianabol because they are already quite toxic and if you combine them, the toxicity will increase exponentially and cause serious damage to your body.

Primobolan cycle can be a reason for the next side effects:

  1. acne
  2. accelerated hair loss
  3. body hair growth
  4. virilization in women(manifested by hair growth in various areas of the body, a deepenedvoice and an enlargement of the clitoris),
  5. a mild enhancement of blood pressure levels
  6. violations of cholesterol levels
  7. curbing of testosterone production
  8. hepatic stress
  9. a low level of liver toxicity


Results wise, users should expect extreme strength increases and weight gain in a relatively short 2-4 week period. Weight gain upwards of 20lbs in 4 weeks is not unheard of with this incredibly potent compound. Although subcutaneous water gain would be minimal, intramuscular water retention should be expected. This is due to inhibition of 11b-hydroxylase and build-up of mineralcorticoids which encourage salt and water retention within the muscles. The most obvious physical effects will be improved vascularity, aggressive muscular pumps, and oily skin.
While methyldrostanolone can stack well with most other steroids, it should never be stacked with another methylated (17aa) steroid.

However, the Anavar steroid was discontinued by Searle in 1989, due to the bad press brought on by bodybuilders abusing the drug. It was later reintroduced to the world market as Oxandrin in 1995, but it remains a controlled substance under US law. The current manufacturer of oxandrolone holds all the rights to their medicine, and that’s why it is very rare to find oxandrolone today. It’s still called Anavar by most people, and it’s very hard to buy. Even if you do find Anavar for sale, the law of supply and demand inevitably results in a rather exorbitant price for the steroid.

Anavar and liver toxicity

anavar and liver toxicity


Results wise, users should expect extreme strength increases and weight gain in a relatively short 2-4 week period. Weight gain upwards of 20lbs in 4 weeks is not unheard of with this incredibly potent compound. Although subcutaneous water gain would be minimal, intramuscular water retention should be expected. This is due to inhibition of 11b-hydroxylase and build-up of mineralcorticoids which encourage salt and water retention within the muscles. The most obvious physical effects will be improved vascularity, aggressive muscular pumps, and oily skin.
While methyldrostanolone can stack well with most other steroids, it should never be stacked with another methylated (17aa) steroid.

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